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Journal of Global Health

● International Society of Global Health

Preprints posted in the last 90 days, ranked by how well they match Journal of Global Health's content profile, based on 21 papers previously published here. The average preprint has a 0.03% match score for this journal, so anything above that is already an above-average fit.

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National Prevalence and Determinants of Concurrent Wasting and Stunting among Under-Five Children in Yemen: Evidence from the 2022-2023 Multiple Indicator Cluster Survey

Salman, A.; Sunzida, R.; Kabir, B.; Das Gupta, R.

2026-10-08 nutrition 10.64898/2026.10.06.26364923 medRxiv
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Background Concurrent wasting and stunting (WaSt) is a severe form of child undernutrition, linked to higher mortality and long-term negative health outcomes. Malnutrition is a significant challenge in Yemen, where the country is experiencing a long-standing conflict, food insecurity, and socioeconomic deprivation. But there is still limited evidence on the burden and determinants of WaSt in Yemen on a national level. This study aimed to estimate the prevalence and identify factors associated with WaSt among children under 5 years in Yemen. Methods We conducted a cross-sectional analysis using nationally representative data from the 2022-2023 Yemen Multiple Indicator Cluster Survey (MICS). A significantly large dataset of 17,734 children aged 0-59 months from all the 22 governorates of Yemen was analyzed. Concurrent wasting and stunting (WaSt) was defined as the coexistence of a weight-for-height z-score (WHZ) below -2 standard deviations and a height-for-age z-score (HAZ) below -2 standard deviations from the WHO Child Growth Standards in the same child. Survey-weighted logistic regression was performed to analyze the factors associated with WaSt among the under 5 children in Yemen. Results The national prevalence of WaSt was 8.4% (95% CI: 7.6-9.2). The highest prevalence of WaSt was found in children aged 12-23 months (12.0%) and in the Western Coastal region (11.6%). After adjustment, male sex (AOR 1.52, 95% CI: 1.30-1.80), residence in the Western Coastal (AOR 2.00, 95% CI: 1.60-2.40), Eastern (AOR 2.00, 95% CI: 1.50-2.70), and Southern regions (AOR 1.60, 95% CI: 1.20-2.10), poorest household wealth (AOR 1.96, 95% CI: 1.30-2.90), moderate (AOR 1.51, 95% CI: 1.13-1.94) and severe food insecurity (AOR 1.94, 95% CI: 1.40-2.60), and recent diarrhoea (AOR 1.22, 95% CI: 1.02-1.44) were associated with higher odds of WaSt. Having a handwashing facility and improved sanitation were protective. Conclusion At least 1 in every 12 under-five children in Yemen was affected by WaSt, and there were significant socioeconomic, geographic, food-security and WASH-related factors influencing this devastating outcome. Instead of simple, one-dimensional approaches, multi-sectoral interventions are needed to address this adversity. And those efforts must be integrated into the system, interconnected with each other and specifically targeted to vulnerable children and households.

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Maternal Functional Difficulty and Child Undernutrition in Malawi:A Nationally Representative Cross-Sectional Study( 2024 DHS)

Samu, G. C.; Karki, R.; Ng'ambi, N. C.; Abiona, M. M.; Karki, S.; Samu, S.; Karki, B. K.; Mphemvu, G.

2026-08-05 nutrition 10.64898/2026.08.03.26359624 medRxiv
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Abstract Background: Maternal disability can reduce the ability to provide adequate care and increase the likelihood of undernutrition among children. In Malawi, over one third of under-five children are affected by stunting. There has been no study that assessed the association between maternal functional difficulty and undernutrition among children in Malawi. The objective was to assess if maternal functional difficulty is associated with stunting, underweight, and wasting in children in Malawi. Methods: Data were extracted from the nationally representative cross-sectional Malawi 2024 Demographic and Health Survey (MDHS). Mother-child dyads were included for mothers aged 15-49 years and children aged [&le;] 59 months, with valid anthropometric z-scores. Maternal functional difficulty was assessed using the Washington Group Short Set on six domains (seeing, hearing, walking, cognition, self-care, communication) and classified as severe vs. no difficulty. Child undernutrition was defined as height-for-age z-score (HAZ) < -2 (stunting), weight-for-age z-score (WAZ) < -2 (underweight), and weight-for-height z-score (WHZ) < -2 (wasting). Survey-adjusted multivariable logistic regression models were fitted, accounting for complex sampling design whilst population attributable fraction was calculated. Results: A total of 4,361 mother-child dyads were analyzed for this study. The overall weighted prevalence of maternal functional difficulty was 3.74% (SE 0.35). There was a reported 36.4% prevalence for child stunting, 8.7% for underweight and 1.7% for wasting. Maternal functional difficulty was not associated with child stunting (AOR 0.85, 95% CI: 0.55-1.33), underweight (AOR 1.06, 95% CI: 0.55-2.02) and wasting (AOR 0.96, 95% CI: 0.26-3.53) after adjustments for confounders. The population-attributable fractions were also found to be negligible for all three nutrition outcomes. Maternal height [&ge;] 150 cm showed strong protective effect against child stunting (AOR 0.29, 95% CI: 0.16-0.54) as well as belonging to the richest wealth quintile (AOR 0.61, 95% CI: 0.42-0.89). In conclusion, there was no statistically significant association between maternal functional difficulty and child undernutrition in Malawi. The family and community support networks in Malawi may be buffering the nutritional effects of maternal disability on children. To reduce child undernutrition in Malawi, efforts should focus on maternal height, household wealth and the first 1,000 days interventions.

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Physicians' Industrial Action: An Interrupted Time Series Analysis Assessing Impact in 11 Kenyan Neonatal Units

Manyasi, C.; Paral, M. M.; Wainaina, J.; Okello, G.; Mochache, D. R.; Mwaniki, H.; Muinde, D. M.; Okech, F. O.; Lawn, J. E.; Rhoda, N. R.; Richards-Kortum, R.; Oden, Z. M.; Hirschhorn, L. R.; Bohne, C. A.; Macharia, W. M.; NEST360 Neonatal Inpatient Dataset and Data Systems Collaborative Group and Context Tracker,

2026-10-08 public and global health 10.64898/2026.10.07.26364929 medRxiv
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Background. Skilled healthcare workers are essential for neonatal survival; however, the Kenyan public health system has historically faced strikes compounded by a human resource crisis. Evidence on how strikes affect neonatal care and mortality remains limited. This study evaluated changes in neonatal admissions, clinical care processes, and inpatient mortality associated with 56 days of disruption during the 2024 Kenyan physicians' strike. Methods. We conducted a retrospective interrupted time-series analysis of 12,184 admissions to 11 Kenyan neonatal units implementing with the NEST360 Alliance, recorded in the Neonatal Inpatient Dataset from December 2023 to August 2024. Weekly admissions and inpatient mortality were modeled over a 72-week window (27,638 admissions) using hospital-clustered generalized estimating equations with seasonal terms. Care processes, case fatality, and birthweight-specific mortality were compared across study periods. Results. Weekly admissions fell from 413 to 189 during the strike (incidence rate ratio (IRR) 0.49, 95% confidence interval (CI) 0.31-0.75), approximately 1,700 fewer admissions than expected, and returned to baseline afterward (IRR 1.00, CI 0.81-1.23). Newborns admitted during the strike were of lower birthweight, more often premature, and more often outborn. Admissions fell across all birth-location categories, most steeply among inborn neonates. No measurable change was detected in documented inpatient coverage of care measures, in crude mortality (12.5% to 14.9%; risk ratio (RR) 1.07, CI 0.85-1.33), or in trend-adjusted mortality (IRR 0.88, CI 0.53-1.45). Case fatality among neonates with recorded infection doubled, from 4.7% to 9.6% (RR 2.06, CI 1.18-3.58; adjusted p = 0.047). Conclusions. The 2024 physicians' strike was associated with severe disruption to neonatal service utilization, with admissions returning to baseline when the strike ended. Among newborns who continued to reach care, inpatient mortality did not change measurably, but case fatality among those with recorded infection doubled. This analysis was confined to inpatient data; hence, the outcomes of newborns who did not reach the hospitals were not captured. Both inpatient and population-level data are needed to assess the full impact of the strike. Mitigating harm during future labor disruptions requires interventions such as resilient care models, formalized task-shifting protocols, and minimum service coverage agreements.

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The Right to Sexual and Reproductive Health among Migrant Workers in Taiwan: Stakeholder Perspectives through an AAAQ Analysis

Tang, P.; Lu, M. W.-H.; Yeung, K.-T.; Guo, B. J.; Wei, K.-F. N.

2026-08-31 public and global health 10.64898/2026.08.26.26361458 medRxiv
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Background Global labor migration from LMIC to higher-income destinations has expanded rapidly, placing increasing pressure on destination-country health. Existing research on cross-border migrant workers has focused largely on occupational health, general healthcare utilization, and disease-specific risks, while there is considerably less evidence on their sexual and reproductive health. This study contributes to this understudied field by examining the policy and health-system factors that shape the sexual and reproductive health services for migrant workers in Taiwan. Methods A qualitative study was conducted in Taiwan between November 2025 and August 2026. 22 stakeholders were purposively recruited from academia, healthcare, nongovernmental organizations, government, labor brokerage, and employers. Data were collected through semi-structured interviews and small focus groups. Interviews were conducted in Mandarin Chinese, transcribed verbatim, and translated into English. Data were analyzed using framework analysis combining deductive coding based on the AAAQ framework with inductive coding of implementation and contextual themes. Results Gaps were identified across all four AAAQ dimensions. Participants described limited migrant-responsive SRH programming; physical, financial, administrative, social, and information barriers; shortcomings in linguistic and cultural responsiveness; and weaknesses in interpretation, coordination, and continuity of care, despite generally favorable views of Taiwan's clinical quality. Conclusions Our findings show that broad insurance coverage and strong clinical capacity do not by themselves ensure the realization of migrant workers' SRHR. In Taiwan, rights were mediated through labor brokerage, gendered live-in work arrangements, and fragmented governance across health, labor, immigration, and social-welfare systems. Improving migrant SRHR therefore requires stronger implementation of existing protections, reduced dependence on informal intermediaries, and more integrated institutional responsibility for cross-sector migrant health needs.

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Health Insurance and Maternal Healthcare Utilisation in Nepal: Evidence from the Nepal Demographic and Health Survey 2022

Lamsal, Y. R.; Hussen, A. M.; Browne, J. L.; Sagtani, R. A.

2026-09-30 public and global health 10.64898/2026.09.29.26364291 medRxiv
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Background: Access to maternal healthcare services is essential for improving maternal and neonatal health outcomes. Health insurance can reduce financial barriers to healthcare access and may facilitate utilisation of maternal health services, and contextualized evidence can further support policy development and implementation. This study assessed the association between health insurance coverage and utilisation of antenatal care (ANC), institutional delivery, skilled birth attendance and postnatal care (PNC) services among women in Nepal. Methods: This study used data from the 2022 Nepal Demographic and Health Survey (NDHS), a nationally representative cross-sectional survey. The analysis included women aged 15-49 years who had a live birth within the 24 months preceding the survey. Inverse probability of treatment weighting (IPTW) based on propensity scores was applied to balance measured socioeconomic and demographic characteristics between insured and uninsured women. Weighted marginal structural models were used to estimate the association between health insurance coverage and maternal healthcare utilisation outcomes. Robustness was assessed using alternative propensity score specifications and E-values for unmeasured confounding. Results: Among 14,845 women interviewed, 2,078 reported a recent live birth and were included in the analysis (unweighted; 1,998 when survey-weighted). Of these, 201 (9.7%) had health insurance coverage and 1,877 (90.3%) were uninsured. After adjustment using IPTW, health insurance coverage was associated with significantly higher utilisation of maternal healthcare services. Insured women had more than twice the odds of attending at least four ANC visits compared with uninsured women (AOR 2.14; 95% CI 1.15-3.98). Similarly, insured women had higher odds of receiving a PNC check-up within two days of delivery (AOR 2.05; 95% CI 1.28-3.27) and receiving PNC from a skilled provider (AOR 1.94; 95% CI 1.23-3.06). Although insurance coverage was positively associated with institutional delivery (AOR 1.55; 95% CI 0.91-2.62) and skilled birth attendance (AOR 1.57; 95% CI 0.90-2.72), these associations did not reach statistical significance. Conclusion: Health insurance coverage was associated with greater utilisation of antenatal and postnatal healthcare services among women in Nepal. However, no significant association was observed for institutional delivery or skilled birth attendance. Expanding health insurance coverage, particularly among underserved populations, may help improve maternal healthcare utilisation and support progress towards universal health coverage and maternal health-related Sustainable Development Goals.

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Continuum of Maternal Healthcare and Neonatal Mortality in Sub-Saharan Africa

Senanu, J.; Dotse, P. F.; Ephson, E. O. E. O.

2026-08-18 public and global health 10.64898/2026.08.17.26360589 medRxiv
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Background: Neonatal mortality remains a significant public health challenge in Sub Saharan Africa (SSA). The continuum of maternal care (COC), spanning antenatal care (ANC), skilled birth attendance (SBA), and postnatal care (PNC) represents an integrated pathway to improving neonatal survival. Multi-country evidence on how adherence to this full continuum affects neonatal outcomes across SSA is limited. Objectives: This study aimed to: (1) construct a composite COC indicator and describe its sociodemographic distribution; (2) estimate its association with neonatal mortality; (3) conduct a counterfactual analysis; and (4) examine cross country heterogeneity in the COC effect on neonatal mortality. Methods: Pooled Demographic and Health Survey (DHS) data from 35 SSA countries (2010 to 2026) were analyzed (N = 867,984 live births). A binary CoC indicator (coc1 = 1 if mother received [&ge;]4 ANC visits, skilled birth attendance, and PNC within 48 hours) was constructed. Survey-weighted logistic regression adjusted for wealth, education, residence, parity, maternal age, child sex, child age, and country. Counterfactual predictive margins and a COC and country interaction model were estimated in Stata 18. Results: Only 13.47% of mothers met the full COC threshold. COC completion was higher among wealthier, urban, more educated, and lower-parity women. After adjustment, CoC receipt was associated with significantly lower odds of neonatal death (aOR = 0.638, 95% CI: 0.577 - 0.706, p < 0.001). Counterfactual analysis showed the predicted neonatal mortality probability would fall from 3.15% (no CoC) to 2.04% (full CoC), an absolute risk reduction of 1.11 percentage points. Cross-country interaction terms were largely non-significant; only Namibia reached significance (p = 0.036). Conclusion: Completion of the full continuum of maternal care is independently associated with reduced neonatal mortality across SSA. Equity focused policies should prioritize integrated service delivery for rural, poor, and less educated women.

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Adult disability and mental/psychological illness in Somaliland socioeconomic inequalities and co-occurrence in the 2020 Somaliland Health and Demographic Survey

Saed, A. A.; Osman, O. A.; Adan, A. M.; Suleiman, Y. I.; Mohamed, A. I.

2026-09-29 public and global health 10.64898/2026.09.24.26363961 medRxiv
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Disability is an important population-health concern, but adult-specific evidence on its distribution and socioeconomic patterning remains limited in Somaliland. This study estimated the prevalence and distribution of reported disability among adults in Somaliland and examined socioeconomic inequality, reported mental/psychological illness, and their co-occurrence. We conducted a cross-sectional secondary analysis of the 2020 Somaliland Health and Demographic Survey. The analysis included 14,579 adults aged [&ge;]18 years who were usual residents, had the disability module administered, and had a defined reported mental/psychological illness measure. Reported disability was defined as at least one positive response across seven disability domains: sight, hearing, speech, learning, mobility, self-care, and mental. Survey-weighted prevalence estimates and design-based comparisons were calculated. Survey-weighted logistic regression assessed associations with household wealth and other covariates. Socioeconomic inequality was assessed using a concentration index and the normalized Erreygers concentration index. Co-occurrence was evaluated by comparing observed joint prevalence with that expected under statistical independence and by survey-weighted logistic regression. The survey-weighted prevalence of any reported disability was 7.30% (95% CI 6.65-8.02). Sight was the most frequently reported domain (3.83%, 95% CI 3.19-4.59), followed by hearing (1.54%, 95% CI 1.20-1.97) and mobility (1.39%, 95% CI 1.14-1.70). Disability prevalence increased markedly with age, from 4.15% among adults aged 18-29 years to 23.96% among those aged [&ge;]60 years. The crude wealth pattern was non-monotonic and was not statistically detectable after adjustment for residence and region. The concentration index for reported disability was 0.0584 (SE 0.0284, p=0.0415). Reported mental/psychological illness had a weighted prevalence of 0.71% (95% CI 0.50-1.00). Both reported disability and reported mental/psychological illness occurred in 0.5032% of adults, compared with 0.05185% expected under statistical independence; the observed-to-expected ratio was 9.70 (95% CI 7.60-11.81). After adjustment for age group and sex, reported disability was strongly associated with reported mental/psychological illness (OR 42.99, 95% CI 18.45-100.18). Reported disability affected approximately one in fourteen adults in Somaliland and showed a marked age gradient and substantial geographic variation. The crude socioeconomic pattern was attenuated after adjustment for geographic context, while concentration analysis indicated modest marginal concentration toward higher wealth ranks. Reported mental/psychological illness was uncommon but co-occurred with reported disability more often than expected under independence. These findings provide an adult population baseline for Somaliland while highlighting the need to distinguish survey-reported disability from the separate mental/psychological illness construct and to interpret the findings within the limitations of cross-sectional, survey-reported measures.

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Dual Burden of Malnutrition Among Mother-Child Dyads in Mozambique: Findings from the Demographic and Health Survey 2022-2023

Shakurun, N.; Andre, F.; Muhajarine, N.

2026-08-10 public and global health 10.64898/2026.08.07.26359956 medRxiv
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Introduction: Nutritional challenges are a global public health concern, especially among children under five in sub-Saharan African countries. The coexistence of an overweight/obese mother and an underweight child in the same household is recognized as a dual burden of malnutrition (DBM). Our study aimed to examine the prevalence and associated factors of DBM among mother-child dyads in Mozambique. Methods: We used nationally representative, cross-sectional data from the Mozambique Demographic and Health Survey 2022-2023 (n=3,605 mother-child dyads). The children's undernutrition condition and maternal BMI status were calculated using the WHO standard reference guidelines. The outcome variable, dual burden of malnutrition, was then created if the children had any undernutrition condition (stunting, wasting, or undernutrition) and the corresponding mother was overweight/obese. Multivariable binary logistic regression, Erreygers's concentration index, and concentration curve were analyzed to determine associated factors and social inequalities. Results: The prevalence of the dual burden of malnutrition was about 5.51%. Mothers aged [&ge;]34 years [aOR (95% CI): 4.01(1.44, 11.14); p<0.05] and mothers with four or more children [aOR (95% CI): 2.68(1.29, 5.57); p<0.05] had higher odds of DBM. Rural residence and using unimproved toilet facilities (latter an indicator) were also significantly associated with experiencing DBM. Additionally, maternal age modified the association between women's empowerment and mother-child DBM. Women aged 15-19 years at the lowest and highest empowerment levels were more likely to experience DBM compared to women 20 years or older. A positive and statistically significant concentration index indicates that wealth-related inequalities exist, with DBM more concentrated among wealthier mother-child dyads. Conclusion: Our study highlights the persistence of household-level DBM in Mozambique. These findings emphasize the need for targeted interventions addressing social and economic inequalities, including poor sanitation marker of broader household deprivation. Prioritizing integrated maternal-child nutrition interventions within national strategies is essential to improving equity in nutrition and health outcomes.

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Satisfaction levels with antenatal care services among postnatal women attending public hospitals in Sana`a City Yemen

AL-Wadhaf, A. F.; Al-Rabeei, N. A.; Hafed, G. I.; Al-Sofiani, L. S.; Al-Jadi, E. H.

2026-09-08 public and global health 10.64898/2026.09.04.26362239 medRxiv
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Background Women`s satisfaction with antenatal care (ANC) is an important indicator of maternal healthcare quality and is associated with the utilization of maternal health services. Identifying factors associated with satisfaction can help inform improvements in ANC service delivery. The study aims to assess women's satisfaction and examine factors associated with ANC satisfaction among postnatal women attending public hospitals in Sana`a City, Yemen. Methods A descriptive cross-sectional study was conducted among 232 postnatal women attending three public hospitals in Sana`a City, Yemen. Participants were proportionally allocated across the three hospitals according to delivery volume, and eligible postnatal women were recruited consecutively until the required sample size was achieved. Data were collected through face-to-face interviews using a structured questionnaire. Descriptive statistics summarized participants` characteristics and satisfaction levels. Chi-square tests assessed associations between categorical variables, and variables with p<0.05 in bivariate analysis were included in multivariable regression. Adjusted Odds Ratio (AORs) with 95% confidence intervals (CIs) were calculated, with statistical significance set at p<0.05. Results Overall, 105 of 232 women (45.3%) were classified as highly satisfied and 127 (54.7%) as having low satisfaction based on the median split. Several factors were independently associated with women's satisfaction. Attendance at ANC education sessions was significantly associated with higher satisfaction, with women who attended sessions more likely to report satisfaction (AOR=6.60, p<0.001). Women with four or fewer children had higher odds of satisfaction (AOR=3.07, p=0.026). Waiting times of less than 30 minutes were associated with higher odds of satisfaction (AOR=3.14, p=0.024), while receiving a delivery plan was also positively associated with satisfaction (AOR=2.77, p=0.009). Residence and education were not significantly associated with women`s satisfaction after adjustment. Conclusions Women's satisfaction with ANC was mainly associated with service-related and obstetric factors. Strengthening ANC education, reducing waiting times, and improving individualized care planning may improve women's satisfaction with ANC services.

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Effect of Continuum of Maternal Healthcare on Neonatal Mortality in Sub-Saharan Africa: A Pooled DHS-8 Analysis

Camara, S.; Dwomoh, D.; Tettey, P.; Barrow, A.

2026-08-21 public and global health 10.64898/2026.08.18.26360750 medRxiv
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Background: Neonatal mortality remains disproportionately high in sub-Saharan Africa (SSA), accounting for nearly half of all deaths in children under five. Although antenatal care, skilled birth attendance, and postnatal care are individually associated with improved newborn survival, few studies have examined whether their integrated receipt as a continuum of care (CoC) confers additional protection against neonatal death, particularly after accounting for sociodemographic confounding and heterogeneity across country contexts. Methods: A pooled cross-sectional analysis was conducted using DHS-8 Births Recode files from five countries: Nigeria (2024), Mali (2023-2024), Congo DRC (2023-2024), Kenya (2022), and Lesotho (2023-2024). The analytical sample comprised 37,351 births within the 36-month postnatal care reference window. Complete CoC was defined as receipt of adequate antenatal care ([&ge;]4 visits with first-trimester initiation), skilled birth attendance, and postnatal care within 48 hours for the mother or newborn. Neonatal mortality was defined as death within 27 days of birth. Survey-weighted logistic and log-Poisson regression models estimated adjusted odds ratios (aOR) and adjusted prevalence ratios (aPR). G-computation quantified the population attributable fraction (PAF). Country-specific heterogeneity was examined through random-effects meta-analysis (DerSimonian-Laird method) and a two-level multilevel logistic regression model. Results: The overall neonatal mortality rate was 29.3 per 1,000 live births (95% CI: 27.6-31.0). Complete CoC prevalence was 19.2% (95% CI: 18.5-19.9%), ranging from 7.8% in Congo DRC to 47.8% in Lesotho. In unadjusted analysis, complete CoC was associated with a 24% reduction in neonatal death odds (cOR: 0.764, 95% CI: 0.583-1.000, p = 0.050). After adjustment for wealth, education, residence, parity, maternal age, child sex, and country, the association was substantially attenuated and non-significant (aOR: 0.961, 95% CI: 0.717-1.289; aPR: 0.962, 95% CI: 0.722-1.282). The PAF under universal complete CoC was 3.2%. The pooled meta-analytic estimate was aOR 0.718 (95% CI: 0.447-1.152), with moderate heterogeneity (I{superscript 2} = 38.9%; {tau}{superscript 2} = 0.089). Country-specific estimates ranged from aOR 0.455 (95% CI: 0.256-0.810) in Kenya to 1.447 (95% CI: 0.496-4.220) in Lesotho. Conclusion: Complete continuity of maternal healthcare was not independently associated with reduced neonatal mortality after full adjustment, suggesting that the unadjusted benefit was attributable to sociodemographic selection rather than a direct causal pathway. These findings underscore the insufficiency of service utilisation metrics in isolation and highlight the need to address the structural and contextual determinants that simultaneously constrain both care access and neonatal survival. Country-level heterogeneity in the CoC-mortality relationship points to the importance of tailored, context-specific interventions.

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Malnutrition and Micronutrient Deficiency among Pregnant Women under Pradhan Mantri Surakshit Matritva Abhiyan in Jharkhand, India: A Cross-sectional Study

Kumari, A.; Kiran, K. A.; Hembrom, S. S.; Kujur, M.; Sinha, R.; Anit, A. K.

2026-08-22 nutrition 10.64898/2026.08.19.26360853 medRxiv
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Objective: Malnutrition and micronutrient deficiency are significant public health problems affecting the well-being of both the mother and her offspring. It is important to first quantify their burden in underserved communities and then to tackle this problem. The objective of this study was to assess the nutritional status, micronutrient deficiency profile, and associated determinants among pregnant women attending antenatal care clinics under PMSMA in selected government health facilities across three districts of Jharkhand, India. Design: The study employed a cross-sectional study design to assess the burden of malnutrition and micronutrient deficiency among pregnant women. Setting: The study was conducted in 4 health facilities in 3 districts of Jharkhand. The selected facilities were Rajendra Institute of Medical Sciences (RIMS), Ranchi; District Hospital (Sadar), Ranchi; District Hospital (Sadar), Godda; and Community Health Centre (Gamharia, Saraikela) under RHTC, Department of Community Medicine, Manipal Tata Medical College, Jamshedpur. The study was conducted during the period of September to December, 2022. Participant: Eligible pregnant women attending ANC clinics under PMSMA in the selected health facilities were enrolled until the required sample size of 977 was achieved. Pregnant women who were critically ill or those who presented with some emergency conditions were excluded from the study. Result: Based on BMI assessment, 38.6% of participants were malnourished, with 17.7% being underweight and 20.9% overweight or obese. Anaemia affected 69.3% of women, while clinical features suggestive of iron deficiency were observed among 21.1% of the participants. Vitamin A deficiency, iodine deficiency, and fluoride excess were also identified among a smaller proportion of women. Conclusion: The present study highlights a substantial burden of both malnutrition and micronutrient deficiency among pregnant women in Jharkhand and justifies the need for integrated maternal nutrition strategies during antenatal care.

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Geography of child stunting and wasting in Bangladesh: a cross-sectional spatial analysis of the 2025 Multiple Indicator Cluster Survey

Hoque, S. M. A. U.; Islam, M. K.; Hasan, M. K.; Sharif, M. M.; Naher, T.; Banu, B.; Hossain, Z. Z.; Baset, K. u.

2026-10-05 public and global health 10.64898/2026.10.02.26364425 medRxiv
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Background. Stunting and wasting drive child mortality and are central to Sustainable Development Goal target 2.2. In 2025, 24.0% of Bangladeshi children under five were stunted and 12.9% wasted, meeting the national stunting target but missing the 8% wasting target. We compared where the two occur and tested whether environmental factors explain the patterns. Methods. We linked the 2025 Bangladesh Multiple Indicator Cluster Survey to cluster GPS locations and environmental data. Moran's I tested clustering and Getis-Ord Gi* found hotspots across 64 districts and 3,144 clusters. We tested whether six environmental and access factors explained the hotspots, estimated what share of affected children each hotspot list reached, and used a joint model to compare factor associations between outcomes. Results. Stunting clustered by region (district Moran's I 0.21, P=0.002), with a north-eastern hotspot centred on Sylhet and Sunamganj. Six environmental factors together removed this clustering (I -0.01, P=0.45) and about 60% of between-district variation (95% CI 28 to 84), more than rainfall alone, with the gain over generic regional terms uncertain. Wasting showed no clear regional clustering (I 0.05, P=0.17), and district stunting and wasting rates were unrelated (r -0.01). Stunting hotspot districts held 5.9% of wasted children, the same as their 5.9% population share. Children with both conditions (902 cases) did not cluster. Altitude and rainfall related differently to stunting than to wasting (all P<0.004), but altitude associations were sensitive to how altitude was modelled. Conclusion. Stunting in Bangladesh is concentrated in the north-east, and six environmental and access factors together account for much of this, though no single factor, including rainfall, does. Wasting shows no clear regional pattern. A stunting hotspot list reached no more wasted children than population share, so surveillance may need both measures, with finer-scale data for wasting.

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Age trajectories of infant mortality among Palestinian refugees born in 2010-2020: evidence from electronic health records

Koksal, S.; Chen, Y.; Jamaluddine, Z.; Akihiro, S.; Checchi, F.; Campbell, O.; Aburto, J. M.

2026-09-23 public and global health 10.64898/2026.09.22.26363685 medRxiv
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ObjectivesTo estimate age trajectories of infant mortality among Palestinian refugees using electronic health records, addressing the scarcity of reliable mortality data in forced displacement settings. SettingPalestinian refugees living in Gaza, West Bank, Jordan, Syria and Lebanon. DesignWe fitted a Bayesian Negative Binomial model to observed death counts, using a flexible parametric function (a shifting power function) to capture the shape of the infant mortality curve, across strata to infer age trajectories of infant mortality. ParticipantsPalestinian refugees born in 2010-2020 and registered with UNRWA health services in Gaza, West Bank, Jordan, Syria and Lebanon. The sample was stratified by sex, field, gestational age and birth cohort. Main outcome measuresSurvival rate to age 1. ResultsOverall, the survival rate to age 1 was 98.64%, with slightly lower rates for males (98.57%) than females (98.68%). Across settings, West Bank refugees had the lowest infant mortality (99.08% survival rate), and Jordan refugees had the highest (98.22% survival rate). Results by gestational age showed a 98.85% survival rate at age 1 among term births compared to a 73.32% survival rate among very preterm births. Survival rates by cohort (births up to 2015 or after) were 98.78% and 98.42%, respectively. ConclusionOur findings highlight the potential of electronic health records for mortality monitoring in forced displacement settings as they reveal consistent mortality trajectories by sex and gestational age, while identifying meaningful variation across refugee settings and subgroups. Summary boxesO_ST_ABSWhat is already known in this topicC_ST_ABSWe searched PubMed and Google Scholar for articles published between Jan 1, 2000, and Feb 20, 2026, in English, using the terms "Palestinian refugees," "infant mortality," "neonatal mortality," and "UNRWA." We found a handful of studies estimating infant mortality among Palestinian refugees, mostly based on household surveys (eg, MICS, national statistical office surveys) or UNRWA surveys using preceding birth techniques. The preceding birth technique has notable limitations, including recall bias, small sample sizes, and selection bias. The majority of these studies focus exclusively on Palestinian refugees residing in Gaza. Estimates for Gaza suggest a sustained decline, from around 127 deaths per 1,000 births in 1960 to 20.2 per 1,000 births in 2006, with a slowdown thereafter and an increase in more recent years. A combined estimate (excluding Syria) across four settings where Palestinian refugees reside measures infant mortality at 18 per 1,000 births in 2011. What this study addsThis study uses a unique data linkage bringing together UNRWAs obstetric and child health records, providing more extensive information and a larger sample size than previous studies. This is also the first study to assess the data quality of these electronic records and to estimate age trajectories of infant mortality among Palestinian refugees. We developed a statistical strategy that estimated infant mortality trajectories covering all five UNRWA fields (Gaza, Jordan, Lebanon, Syria, and the West Bank) for children born in 2010-2020, and examined differences across subpopulations by sex, field, gestational age and cohort.

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Facility-based abortion care in India's public health system: 14-year trends, geographic inequalities, and the impact of the 2021 MTP Amendment Act

Mishra, V.; Parihar, K. S.

2026-09-08 public and global health 10.64898/2026.09.06.26362364 medRxiv
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Background: In 2021, India amended its Medical Termination of Pregnancy (MTP) Act, expanding gestational limits up to 24 weeks for vulnerable categories and removing the requirement for a second medical opinion up to 20 weeks. We investigated 14-year trends in facility-reported MTPs, geographic access gaps, and whether the 2021 amendment changed late-gestation service provision. Methods: Analysis of monthly district-level HMIS reports, fiscal years 2008-09 to 2021-22. We extracted total facility MTPs, early ([&le;]12 weeks) and later (>12 weeks) gestation procedures, post-abortion contraception adoption, and districts reporting zero MTPs. Interrupted time-series models evaluated COVID-19 disruption and post-2021 amendment shifts. Results: Public facilities recorded 8.9 million MTPs over 14 years, with annual totals holding flat at 0.60-0.75 million, representing a small fraction of India's estimated true abortion incidence. Persistent geographic disparities were documented: ~5% of all districts reported zero public facility MTPs annually. Following the September 2021 notification of MTP Amendment Rules, public facilities recorded a rapid 55% surge in >12-week procedures above pre-amendment trends, raising the late-gestation share from 6.9% to 9.7%. Post-abortion contraception provision experienced a deep 50% collapse during the 2020 lockdown that failed to recover through 2022. Conclusion: Routine service records provide the first empirical evidence that the 2021 MTP Amendment Act successfully expanded facility access to later-gestation abortion care. However, flat overall public reporting and persistent zero-reporting district clusters highlight severe lingering supply-side barriers and an unmet need for post-abortion family planning integration.

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Roles, Challenges, and Solutions for Maternal and Child Health in rural Communities in Bangladesh

Abdullah, A. S.; Halim, A.; Haq, F.; Sayem, A. S. M.; Dalal, K.

2026-10-21 public and global health 10.64898/2026.10.18.26365859 medRxiv
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Background Despite substantial improvements in maternal and child health over the past two decades, preventable maternal and neonatal morbidity and mortality remain major public health concerns in rural Bangladesh. Community-based interventions involving Community Volunteers (CVs), Community Groups (CGs), and Community Support Groups (CSGs) have been introduced to strengthen maternal and child health (MCH) services through health promotion, community engagement, and improved linkage with primary healthcare facilities. This study explored the roles, challenges, and opportunities of these community-based platforms in improving maternal and child health services. Methods A qualitative study was conducted in Kalaroa Upazila of Satkhira District, Bangladesh, between July and October 2020. Data were collected through focus group discussions and in-depth interviews with mothers, Community Volunteers, Community Group members, and Community Support Group members. Participants were purposively selected to capture diverse experiences from intervention and comparison areas. Interviews were conducted using semi-structured guides, audio-recorded with informed consent, transcribed verbatim, translated into English, and analyzed thematically using an inductive approach. Results Participants from intervention areas demonstrated greater knowledge of birth preparedness, antenatal care, pregnancy danger signs, institutional delivery, postnatal care, and newborn care than those from comparison areas. Community Volunteers, CGs, and CSGs played important roles in identifying pregnant women, conducting household counselling, promoting skilled maternal healthcare, facilitating referrals, and strengthening community participation. Participants perceived that these activities increased maternal awareness, improved health-seeking behaviour, and enhanced utilization of maternal and newborn health services. However, persistent barriers, including socio-cultural beliefs, financial constraints, transportation difficulties, shortages of skilled healthcare providers, and inadequate logistical support for community volunteers, continued to limit equitable access to quality services. Participants recommended strengthening community awareness programmes, improving community clinic readiness, enhancing referral systems, and providing regular training and supportive supervision for community-based health workers. Conclusions Community-based maternal health interventions involving Community Volunteers, Community Groups, and Community Support Groups contribute to improved maternal knowledge, health-seeking behaviour, and utilization of essential maternal and newborn health services in rural Bangladesh. Sustaining these gains will require stronger primary healthcare services, continued community engagement, and targeted strategies to address persistent health system and socio-cultural barriers. These findings provide important evidence for strengthening community-based maternal and child health programmes in Bangladesh and similar resource-constrained settings.

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Spatiotemporal dynamics, factors associated with neonatal mortality and health interventions in Mali: a modeling study

TRAORE, F. B.; Sidibe, C. S.; Keita, Y.; Sidibe, F.; Terera, I.; Traore, M.; Berthe, M.; Dembele, H.; Belem, B.; Kone, K.; Toure, A.; Dabo, A.; Diawara, F.; Guindo, I.; Maiga, A.

2026-09-21 public and global health 10.64898/2026.09.17.26363290 medRxiv
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Background Neonatal mortality in Sub-Saharan Africa remains high, accounting for approximately 46% of all neonatal deaths worldwide. In Mali, neonatal mortality stands at 29 deaths per 1,000 live births, with marked subnational disparities. This study aimed to assess the spatiotemporal dynamics of neonatal mortality in Mali from 2012 to 2023 and to project potential reductions in neonatal mortality by 2035 under different scenarios of scaling up three high-impact interventions. Methods We analyzed data from the 2012-2013, 2018, and 2023-2024 Demographic and Health Surveys to assess spatiotemporal patterns in neonatal mortality across Mali. Multilevel mixed-effects logistic regression identified factors associated with neonatal mortality. Global Moran's I and Local Indicators of Spatial Association assessed spatial dependence and identified high-high clusters. The Lives Saved Tool estimated potential reductions in neonatal deaths under alternative intervention scale-up scenarios through 2035. Results National neonatal mortality declined from 34 deaths per 1,000 live births (95% CI: 31-38) in 2012 to 29 (95% CI: 26-32) in 2023. Significant spatial clustering persisted across all survey rounds (Global Moran's I, all p<0.001), with recurrent high-high clusters in Sikasso, Mopti, Segou and Tombouctou. Male neonates had higher odds of death (AOR, 1.66; 95% CI, 1.26-2.19), whereas birth intervals of at least 2 years (AOR range, 0.42-0.48), postnatal care (AOR, 0.42; 95% CI, 0.19-0.94), and improved sanitation (AOR, 0.42; 95% CI, 0.27-0.67) were associated with lower odds. LiST projections indicated that scaling up thermal care, neonatal resuscitation, and clean cord care could avert more than half of preventable neonatal deaths by 2035. Conclusions Persistent clusters of high neonatal mortality were identified in Sikasso, Segou, Mopti, and Tombouctou, highlighting the need for geographically targeted strategies. Scaling up high-impact neonatal interventions could substantially reduce preventable neonatal deaths in Mali.

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Individual-Level Double Burden of Malnutrition among Ethiopian Women: Prevalence, Machine-Learning Prediction and Explainability Using the 2024/25 Ethiopian Demographic and Health Survey

Gebiru, A. M.; Genet, G. B.; Ambelie, S. T.; Mihret, S. A.; Azene, D.; Zeleke, m. e.; Abereha, A. y.; Shibabaw, Y. Y.

2026-09-25 epidemiology 10.64898/2026.09.22.26363745 medRxiv
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ABSTRACT Background: The double burden of malnutrition, combining overweight or obesity with anemia is vital in nutritional transitions. Evidence regarding its national distribution and prediction using routine survey data in Ethiopia remains limited. Objective: To estimate the national prevalence of individual-level double burden of malnutrition among non-pregnant Ethiopian women aged 15-49 years and evaluate machine-learning models using data from the 2024/25 Ethiopian Demographic and Health Survey. Methods: we analyzed 14250 non-pregnant women. Double burden of malnutrition was defined as a body mass index equal to or greater than 25.0 kilograms per square meter with an altitude- and smoking-adjusted hemoglobin concentration below 12.0 grams per deciliter. Data were split into an 80% training set and a 20% holdout test set. Six algorithms were evaluated using cross-validation, while SHapley Additive exPlanations described feature contributions. Results: the weighted national double burden of malnutrition prevalence was 8.4% (95% confidence interval 7.9%-8.9%), higher in urban residents (20.0% versus 4.0%) and the richest wealth quintile (26.7% versus 2.7%). Extreme Gradient Boosting achieved an area under the receiver operating characteristic curve of 0.892 (95% confidence interval 0.875-0.909) and an area under the precision-recall curve of 0.764 outperforming logistic regression (area under the receiver operating characteristic curve of 0.781). Extreme Gradient Boosting sensitivity was 82.1%, specificity was 81.4% and the Brier score was 0.068. Household wealth, residence and respondent age were top predictors. Conclusions; the double burden of malnutrition affected one in twelve non-pregnant Ethiopian women unevenly across groups. Routine characteristics effectively discriminated double burden of malnutrition cases though external validation is needed prior to clinical use.

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Validation of Algorithms to Identify Small or Large for Gestational Age in the Korean Nationwide Healthcare Database

Cho, Y.; Lim, H.; Suh, B.; Lee, Y.; Shin, J.-Y.

2026-09-11 epidemiology 10.64898/2026.09.09.26362678 medRxiv
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Objective: Small for gestational age (SGA) and large for gestational age (LGA) are critical endpoints in perinatal pharmacoepidemiology, yet gestational age is frequently missing in administrative databases. This study validated algorithms for identifying SGA and LGA in the Korean National Health Information Database (NHID). Methods: We linked the NHID with national vaccination and infant health screening registries (2018-2021) to create a validation cohort of 94,159 pregnancies with reference standard gestational age and birth weight; infants with birth weights below the 10th or above the 90th percentile were considered SGA or LGA, respectively. We evaluated four algorithms: ICD-10 diagnosis codes from infant claims (Method A), maternal claims (Method B), either infant or maternal claims (Method C), and birth weight combined with estimated gestational age (Method D). Results: ICD-10-based algorithms consistently underestimated prevalence, showing high specificity but low sensitivity (<17%). In contrast, Method D demonstrated superior performance: for SGA, sensitivity was 89.3%, specificity 96.8%, and positive predictive value (PPV) 71.6%; for LGA, sensitivity was 77.5%, specificity 98.3%, and PPV 84.7%. Conclusion: SGA and LGA can be identified with reasonable accuracy in the NHID using birth weight and estimated gestational age, whereas diagnosis codes alone can underestimate prevalence.

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Not all women are equally at risk: A Demographic health survey (DHS) 2023 based analysis of overweight and obesity inequalities among women in the Democratic Republic of the Congo

SIRI, B. A. A.; Shonganye, J.; Papy, M. K.; Mandja, B.-A.; Mutuale, G. L.; Otshudiandjeka, J. B.; Kazadi, D. M.

2026-08-22 epidemiology 10.64898/2026.08.19.26360799 medRxiv
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Background In sub-Saharan Africa, women are navigating overlapping burdens of undernutrition and rising overweight/obesity, often within fragile health system and rapidly changing food environments. In the DRC, theses tensions may be intensified by rapid urbanization, socioeconomic disparities, insecurity and shifting lifestyles. Despite those changes, national level evidence on who is the most affected by excess weight and why remains scarce. This study assessed the determinant of overweight and obesity among Congolese women of reproductive age, aiming to highlight the social and geographic inequalities. Methods We analysed nationally representative data from the 2023 DHS. The analysis included 10,740 non-pregnant women aged 15-49 years with valid anthropometric measurements. Overweight/obesity was defined as BMI [&ge;] 25 Kg/m2. We examined a broad range of potential associated factors, including province, residence, socioeconomic status, household structure, education level, marital status, occupation, dietary diversity score, healthy diet related indicators, media exposure, internet use and health service utilisation. Weighted analyses accounted for the DHS sampling design. Variables associated at p value < 0.20 were retained for multivariable modelling. Multicollinearity was assed via adjusted GVIFs. Four hierarchical weighted logistic regression were built; the fully adjusted model guided final interpretation. Results Nearly on five women of reproductive age (19.5%) lived overweight or obesity. However, this burden was not evenly distributed. Women from Kongo Central and Tshuapa exhibited significantly lower odds, while those in Bas-Uele, Nord-Kivu, Sud-Kivu and Maniema were substantially more affected, highlighting spatial inequities. Women living in rural areas had lower odds of overweight/obesity compared with their urban counterparts (aOR=0.6; 95% CI: 0.48-0.79; p<0.001). A pronounced socioecomic gradient was observed. Compared with the poorest households, the likelihood of excess weight increases progressively among women in middle income household (aOR=1.65;95% CI:1.13-2.41), rich households (aOR=2.41; 95%CI:1.62-3.60), and was highest among the richest (aOR=4.19; 95%CI: 2.45-7.16). Larger households appeared protective, with lower odds observed in household of 4-5 members (aOR=0.68; 95%CI:0.5-0.92), 6-7 (aOR=0.72;95% CI: 0.54-0.97) and [&ge;]8 members (aOR=0.69; 95%CI:0.50-0.95) compared with smaller household. Age was the strongest predictor, with risk sharply accelerating after 30 years. Being married or in union was associated with higher odds. Notably, frequent internet use independently predicted overweight/obesity. In contrast, dietary diversity and unhealthy food indicators were not significantly significant in the fully adjusted models. Conclusion Overweight and obesity are rising among Congolese women, but unevenly and unjustly. Urban residence, socioeconomic status, age and digital exposure strongly sharply shape who is the most affected, revealing deep social and geographic inequities. Addressing this growing epidemic requires equity-oriented, province specific actions, alongside stronger primary prevention. Key-word: Overweight-obesity-associated factors, DRCongo, DHS

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Implementation of early child development and maternal mental health care package for forcibly displaced Myanmar population in Bangladesh refugee camps: a process evaluation and cost-effectiveness study

Khan, N.; Khan, M. A.; Warraitch, A.; Islam, K.; Khan, M. A.; Khan, S. E.; Azdi, Z. A.; Jahan, I.; Huque, R.

2026-10-06 public and global health 10.64898/2026.10.01.26364288 medRxiv
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Abstract Background: The risk of developmental delays among infants in the refugee camps is high due to prolonged exposure to adverse situations such as poverty, violence, lack of access to basic necessities, safety, poor maternal mental health and inadequate access to healthcare. To reduce the risk of developmental delays, a contextualized early child development and maternal mental health care package, was implemented through enabling and engaging the refugee women as community-based care providers. Methods: The process evaluation study was conducted using a mix-method design to explore the acceptability, feasibility, appropriateness, adoption, and cost of the Early Child Development (ECD) and maternal mental health care package in refugee camps, by applying Proctor et al framework. Data on quantitative indicators was reviewed for 348 mother-child dyads in the intervention arm. Qualitative interviews were conducted with 12 mothers, 5 community health workers, and 2 members of the implementing research team. Incremental Cost-Effectiveness Ratio (ICER) was calculated using the healthcare provider perspective to estimate the incremental cost-effectiveness of the ECD care package in reducing proportion of children with two or more developmental delays. Results: Home-based delivery of counselling sessions was a key facilitator in ensuring the successful implementation of intervention. The delivery of intervention by modestly educated refugee women reduced cultural and language barriers and facilitated the home-based delivery of sessions. Mothers found the recommended activities feasible to do in routine as they were culturally appropriate, and did not require maternal literacy or additional resources. The intervention was cost-effective with an ICER of 63 USD in reducing the proportion of children with two or more developmental delays by one percentage point. Conclusion: Contextualized ECD and maternal health care package is a potentially replicable and scalable intervention for refugee healthcare systems.